Variación estacional de la hemorragia digestiva alta / Seasonal variation of upper gastrointestinal bleeding

Introducción: La hemorragia digestiva alta representa una de las causas más frecuentes de morbilidad y mortalidad en los servicios de cirugía general y específicamente es la primera causa de mortalidad en el servicio, por lo que constituye una emergencia médico-quirúrgica. Objetivo: Identificar la existencia de un patrón estacional en la incidencia de hemorragia digestiva alta en época invernal y estimar la frecuencia de algunos factores de riesgo de esta enfermedad. Métodos: Se realizó un estudio descriptivo, de series temporales, de pacientes afectados por esa enfermedad que acudieron al Hospital Dr. Miguel Enríquez en el periodo comprendido entre diciembre de 2017 y enero de 2020. La muestra quedó conformada por 151 pacientes que presentaron como diagnóstico de ingreso hemorragia digestiva alta. Resultados: Predominó el sexo masculino y los mayores de 60 años. La temporada de mayor incidencia de esta complicación digestiva fue la invernal (diciembre, enero y febrero). Los factores de riesgo que predominaron fueron los hábitos tóxicos y la ingestión de AINES y ASA. La forma de presentación más frecuente fue la melena y la principal etiología la úlcera péptica duodenal. Conclusiones: Los casos con hemorragia digestiva alta predominaron en la temporada invernal y los factores de riesgo más frecuentes fueron los hábitos tóxicos y el uso de AINES en relación con el periodo estacional(AU)

Introduction: The High Digestive Hemorrhage represents one of the most frequent causes of morbidity and mortality in the General Surgery Services and it is specifically the first cause of mortality in our service. It constitutes a very frequent medical-surgical emergency. Objective: To determine the existence of a seasonal pattern in the incidence of HDA in winter and its relationship with risk factors. Methods: A descriptive and retrospective study was carried out with a longitudinal design in which patients affected by HDA were studied. These patients were assisted at "Dr. Miguel Enriquez Hospital" between December 2017 and January 2020. The study group was composed of all the patients who came to our emergency services with manifestations of bleeding from the upper digestive tract. The sample was made up of 151 patients who presented a diagnosis of HDA at the time of their admission. Results: The predominant sex was male and the age over 60 years old. The season with the highest incidence of this digestive complication was winter (December, January and February). The risk factors that predominated in our study were toxic habits and ingestion of AINES, ASA. The predominant form of presentation of the HDA were tarry stools, being the Duodenal Peptic Ulcer the main etiology. Conclusions: Cases with Upper Digestive Bleeding predominated in the winter season and the most frequent risk factors were toxic habits and the use of NSAIDs in relation to the seasonal period(AU)

Clinical features of children with colorectal polyps and the efficacy of endoscopic treatment: an analysis of 1 351 cases / 中国当代儿科杂志

OBJECTIVES@#To study the clinical features of children with colorectal polyps and the efficacy of endoscopic treatment.@*METHODS@#A retrospective analysis was performed on the medical data of 1 351 children with colorectal polyps who were admitted and received colonoscopy and treatment in the past 8 years, including clinical features and the pattern and outcomes of endoscopic treatment.@*RESULTS@#Among the 1 351 children, 893 (66.10%) were boys and 981 (72.61%) had an age of 2-<7 years, and hematochezia (1 307, 96.74%) was the most common clinical manifestation. Of all the children, 89.27% (1 206/1 351) had solitary polyps, and 95.77% (1 290/1 347) had juvenile polyps. The polyps were removed by electric cauterization with hot biopsy forceps (6 cases) or high-frequency electrotomy and electrocoagulation after snare ligation (1 345 cases). A total of 1 758 polyps were resected, among which 1 593 (90.61%) were pedunculated and 1 349 (76.73%) had a diameter of <2 cm. Postoperative complications included bleeding in 51 children (3.77%), vomiting in 87 children (6.44%), abdominal pain in 14 children (1.04%), and fever in 39 children (2.89%), while no perforation was observed. The children aged <3 years had the highest incidence rates of postoperative bleeding and fever (P<0.0125), and the children with a polyp diameter of ≥2 cm had significantly higher incidence rates of postoperative bleeding, vomiting, and fever (P<0.05).@*CONCLUSIONS@#Solitary polyps, pedunculated polyps, and juvenile polyps are common types of pediatric colorectal polyps. Electric cauterization with hot biopsy forceps or high-frequency electrotomy and electrocoagulation after snare ligation can effectively remove colorectal polyps in children, with good efficacy and few complications. Younger age and larger polyp diameter are associated with a higher risk of postoperative bleeding.

Clinical characteristics of paroxysmal nocturnal hemoglobinuria (PNH) complicated with ischemic bowel disease / 中华内科杂志

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease. Gastrointestinal involvement is rarely seen in PNH. This study aims to analyze the clinical features in PNH patients complicated with ischemic bowel disease. Clinical date of 6 patients were collected at Peking Union Medical College Hospital from January 2010 to December 2020. The clinical manifestations, laboratory tests,imaging, endoscopic,and histopathological features and treatment were analyzed.Five in 6 patients were men, with a median age of 31 years old at onset. Most of disease course were recurrent episodes of chronic disease, with abdominal pain (5/6) and gastrointestinal bleeding (5/6). Laboratory examinations showed pancytopenia, reticulocytosis, elevated serum lactate dehydrogenase, high D-dimer and C-reactive protein levels in all patients. Multiple segments of small intestine were the most commonly involved and colon was also affected. Abdominal CT scan showed thickening and roughness or exudation of the intestinal wall (6/6), increased mesenteric density or “comb sign”(4/6), and cholestasis or gallbladder stones (5/6). Endoscopic manifestations included irregular shallow ulcers in the annular cavity (5/6), swelling mucosa with well-defined margins (6/6). Pathological biopsy revealed chronic inflammation of mucosa. The efficacy of steroids combined with anticoagulant therapy was better than that of steroids alone. Ischemic bowel disease in PNH patients is different from typical ischemic enteritis. Young patients, involvement of intestine with multiple segments are common characteristics. The anticoagulant is an essential agent for these patients.

Myeloma coexisting with jejunal light chain amyloidosis

Amyloid Light chain (AL) amyloidosis is a rare disease, which is seen in approximately one-tenth of patients with multiple myeloma. We report a 52 years old male, who presented with complaints of anorexia and weight loss. He was diagnosed to have multiple myeloma-international staging score (ISS) Stage 3 and was started on VTD (Bortezomib, Thalidomide, and Dexamethasone) chemotherapy. Within 2 weeks of therapy, he had abdominal symptoms like abdominal pain, loose stools, vomiting and hematochezia. Imaging showed dilated proximal bowel loops with fluid filled contents and prominent vessels in rectum. Emergency surgical exploration revealed thickened proximal jejunum with blood clots in the lumen. Resection of proximal jejunum was done. Histopathological examination of resected specimen was suggestive of AL amyloidosis. Post-surgical resection of jejunum, patient had initial improvement followed by deterioration. He was discharged against medical advice as per relative’s request. Hence an index of clinical suspicion of amyloidosis must been present in all Multiple myeloma patients.

Concurrent term pregnancy and choriocarcinoma: A case report / Philippine Journal of Obstetrics and Gynecology

@#Term pregnancy with choriocarcinoma is a rare entity and cases where both the mother and fetus survive are even more rare. This paper discusses the case of a term pregnancy with a concomitant choriocarcinoma in a 21 yearold, gravida 2 para 0, who presented with hematochezia on the third trimester. She delivered via cesarean section for non-reassuring fetal status with good neonatal outcome. She underwent exploratory laparotomy postdelivery due to profuse gastrointestinal bleeding associated with deteriorating hemodynamic status. Histopathologic report revealed Ileal Choriocarcinoma. Metastatic work up showed liver and lung metastasis. The patient achieved remission after 8 cycles of EMACO chemotherapy. There was no evidence of recurrence in the subsequent 10 months of regular follow up.

Endometriosis en colon sigmoides asociada a hematoquecia en una paciente histerectomizada / Endometriosis within the sigmoid colon associated with hematochezia in a hysterectomized woman

La endometriosis es la existencia e implantación de estroma y glándulas endometriales funcionales fuera del útero, pero con funcionalidad similar al tejido endometrial dentro de la cavidad uterina. Tiene una presentación clínica variable, ya que depende del sitio de implantación. Se ha determinado que es la tercera causa de hospitalización en los Estados Unidos. Se presenta el caso de una paciente de 44 años de edad con hematoquecia causada por endometriosis profunda infiltrante en colon sigmoides, después de once años de haberse realizado la histerectomía. La paciente fue tratada mediante resección quirúrgica debido a que se sospechaba de un carcinoma.

Endometriosis is the presence of functional ectopic endometrial tissue outside the uterine cavity. The clinical presentation is variable and depends on the location. It is considered the third leading cause of hospitalization in the United States. In this case, we report a 44-year-old woman with hematochezia caused by deep infiltrating endometriosis within the sigmoid colon, after having undergone a hysterectomy 11 years ago. The patient received surgical resection due to suspicion of carcinoma.

Clinical Experience of Professor SHEN Hong for Treating Ulcerative Colitis by Enema / 浙江中医药大学学报

Objective]To summarize professor SHEN Hong’s clinical experience in treating ulcerative colitis with enema prescription.[Method] By following the teacher clinic and sorting out the related cases, the author summarizes professor SHEN Hong’s academic experience of treatment of ulcerative colitis with enema prescription, and for proven cases. [Result]On the base of disease stage, Professor SHEN Hong uses the advantages of external therapy of Chinese medicine, and combines the syndrome differentiation and disease differentiation by the reference to the treatment of abscess,carbuncle. On the acute stage, he uses the elimination method to relieve heat and toxic material, cool blood and eliminate carbuncle. On the remission stage, he uses reinforcing method to support sore and drainage of pus and heal wound and promote tissue regeneration in case of recrudescence. Meantime, he focuses on the different locations of lesions by reasonable enema ways. The medication he uses is concise and the prescription changes flexibly with permitted addition and subtraction. The clinical curative effect is satisfactory. [Conclusion] Professor SHEN Hong’s experience is effective and worthy of inheritance and promotion.

A Case of Cap Polyposis with Epidermal Nevus in an Infant

Cap polyposis is extremely rare in children. We report a case of an 11-month-old male infant who visited our hospital because of rectal prolapse and small amount of hematochezia lasting several days. He also had an epidermal nevus in the sacral area. Colonoscopy showed erythematous, multilobulated, circumferential, polypoid lesions with mucoid discharge from the rectum. He was diagnosed with cap polyposis by endoscopy and histologic examination. He was treated with surgical resection, and was closely followed up. In the relevant literature, there is no report of cap polyposis in an infant. We report the first case of cap polyposis in the youngest infant.

Role of Colonoscopy in Patients with Hematochezia / 대한소화기학회지

BACKGROUND/AIMS: Although colonoscopy is not indicated in patients with hematochezia, many surgeons, internists, and physicians are recommending colonoscopy for these patients in Korea. The aim of this study is to evaluate the diagnostic value of colonoscopy for patients with hematochezia. METHODS: We retrospectively reviewed the data of colonoscopy between January 2010 and December 2010. A total of 321 patients among 3,038 colonoscopies (10.6%) underwent colonoscopy to evaluate the cause of hematochezia. The patients with previous colorectal surgery (2) or polypectomy (5) were excluded. We analyzed endoscopic diagnoses. Advanced neoplastic polyps were defined as adenomas with villous histology or high grade dysplasia, or adenomas more than 10 mm in diameter. RESULTS: Hemorrhoid was the most common diagnosis (217 cases, 67.6%). Polyps were detected in 93 patients (29.0%), but advanced neoplastic polyps were found in only 14 cases (4.4%). Colorectal cancers were diagnosed in 18 patients (5.6%) including 14 rectal cancers. There was no cancer located above sigmoid-descending junction. Diverticuli were detected in 41 patients (12.8%) but there was only one case of suspected diverticular bleeding. Colitis was diagnosed in 24 patients (7.5%). Other lesions included acute anal fissure, rectal tumor, stercoral ulcer, and radiation proctitis. CONCLUSIONS: The colonoscopy had little value in patients with hematochezia because the most pathologic lesions were located below sigmoid colon. The first choice of diagnosis in patients with hematochezia is sigmoidoscopy.

Investigation to the Features in the Treatment of Hemorrhage Syndrome of Lu Yuanlei / 浙江中医药大学学报

Objective] To further investigate the academic thoughts and the aspects of clinical treatments of Lu Yuanlei focused on hemorrhage syndrome. [Methods]According to study straightly the compilation of medical records of Lu Yuanlei and his academic works, the scientific explanation toward the therapeutic methods for hemorrhage syndrome and especially both the theoretical thoughts and the clinical experience of hemoptysis and hematochezia are discussed and concluded. [Results] Lu Yuanlei concluded the three major principles of healing hemorrhage syndrome. To emphasize the importance of patients with sufficient healthy qi inside as well as to make well use of Bupleurum based on syndrome differentiation in the clinical treatments. In addition, with the caution of stopping bleeding without blood stagnation, from our survey, there are three frequently used pairs of drugs specialized for hemostasis in the medical records of Lu Yuanlei. Furthermore, Lu Yuanlei demonstrated three distinguished opinions in the examination of enterorrhagia , to apply Huang Tu Decoction deliberately for the clinical treatment of hematochezia. [Conclusion] The valuable academic inspiration and clinical treatments of hemorrhage syndrome proposed by Lu Yuanlei can be meditated and preached. Besides, his academic viewpoints of scientific connotation of TCM are obviously prominent in the contents.

Clinical characteristics and etiology analysis of 223 children undergoing colonoscopy / 中华实用儿科临床杂志

Objective To investigate the clinical characteristics and etiology in infants undergoing colonoscopy in order to improve the understandings of lower gastrointestinal tract diseases and their endoscopic manifestations.Methods The clinical and endoscopic data of the infants aged ≤ 3 years old who underwent conoloscopy at the Department of Gastroenterology,Children's Hospital of Chongqing Medical University,from July 2010 to December 2014,were retrospectively analyzed.A total of 223 children were included,148 male and 75 female.The age range was from 26 d to 3 years old(＜6 months:41 cases;6-12 months:68 cases;1-3 years old:114 cases).Results A total of 235 colonoscopies were performed under deep sedation by single or double manipulators.Cecal intubation was successful in 192 colonoscopies and terminal ileal intubation was completed in 29 colonoscopies,with a high success rate of 94.0％ (221/235 colonoscopies).The main symptoms included hematochezia (124 cases,55.6％),persistent/chronic diarrhea (55 cases,24.7％),hematochezia with chronic diarrhea(22 cases,9.5％),and others(22 cases,9.5％).Of the 223 patients,clear diagnosis were established for 215 children (96.4％),with food protein-induced proctocolitis (FPIPC) (78/223 cases,35.0％),colonic polyps (50/223 cases,22.4％),colitis (29/223 cases,13.0％),antibiotic associated diarrhea (AAD) (19/223 cases,8.5％),FPIPC with AAD (10/223 cases,4.5％).Conclusions Colonoscopy serves as a very important tool for the accurate diagnosis of lower gastrointestinal diseases with hematochezia and/or chronic diarrhea.FPIPC and colonic polyps are the most common causes for hematochezia and/or chronic diarrhea.AAD may be another important cause of chronic diarrhea and bloody stool in infants.Moreover,ghe application of colonoscopy in combination with histopathology can also play an important role in the diagnosis of some rare diseases,such as intestinal tuberculosis,primary intestinal lymphangiectasia,Behcet's disease and primary immunodeficiency disease.

The Clinical Outcomes of Lower Gastrointestinal Bleeding Are Not Better than Those of Upper Gastrointestinal Bleeding

The incidence of lower gastrointestinal bleeding (LGIB) is increasing; however, predictors of outcomes for patients with LGIB are not as well defined as those for patients with upper gastrointestinal bleeding (UGIB). The aim of this study was to identify the clinical outcomes and the predictors of poor outcomes for patients with LGIB, compared to outcomes for patients with UGIB. We identified patients with LGIB or UGIB who underwent endoscopic procedures between July 2006 and February 2013. Propensity score matching was used to improve comparability between LGIB and UGIB groups. The clinical outcomes and predictors of 30-day rebleeding and mortality rate were analyzed between the two groups. In total, 601 patients with UGIB (n = 500) or LGIB (n = 101) were included in the study, and 202 patients with UGIB and 101 patients with LGIB were analyzed after 2:1 propensity score matching. The 30-day rebleeding and mortality rates were 9.9% and 4.5% for the UGIB group, and 16.8% and 5.0% for LGIB group, respectively. After logistic regression analysis, the Rockall score (P = 0.013) and C-reactive protein (CRP; P = 0.047) levels were significant predictors of 30-day mortality in patients with LGIB; however, we could not identify any predictors of rebleeding in patients with LGIB. The clinical outcomes for patients with LGIB are not better than clinical outcomes for patients with UGIB. The clinical Rockall score and serum CRP levels may be used to predict 30-day mortality in patients with LGIB.

Hematochezia due to Angiodysplasia of the Appendix

Common causes of lower gastrointestinal bleeding include diverticular disease, vascular disease, inflammatory bowel disease, neoplasms, and hemorrhoids. Lower gastrointestinal bleeding of appendiceal origin is extremely rare. We report a case of lower gastrointestinal bleeding due to angiodysplasia of the appendix. A 72-year-old man presented with hematochezia. Colonoscopy showed active bleeding from the orifice of the appendix. We performed a laparoscopic appendectomy. Microscopically, dilated veins were found at the submucosal layer of the appendix. The patient was discharged uneventfully. Although lower gastrointestinal bleeding of appendiceal origin is very rare, clinicians should consider it during differential diagnosis.

Adenocarcinoma colorrectal en una nina de 5 años de edad / Colorectal adenocarcinoma in a 5 year old girl

El adenocarcinoma colorrectal es excepcional en ninos, por lo que, generalmente, se lo diagnostica en estadios avanzados, con mal pronóstico. Presentamos el caso de una nina de 5 anos de edad con proctorragia recurrente de 2 meses de evolución, sin alteraciones en los análisis de laboratorio, en quien se confirmó la existencia de un adenocarcinoma colorrectal por medio de una colonoscopía. La estatificación demostró un compromiso local sin enfermedad o metástasis a distancia. La paciente se trató con resección laparoscópica y quimioterapia adyuvante, y permaneció libre de enfermedad a 21 meses de seguimiento.

Colorectal adenocarcinoma is exceptional in children, generally diagnosed in advanced stages, with worse prognosis. We report the case of a 5 year old girl with isolated hematochezia lasting two months without other findings, in whom a colorectal adenocarcinoma was confirmed by colonoscopy. Staging revealed localized disease, extending to perisigmoid fat and a few adjacent ganglia. She was treated by laparoscopic resection and adjuvant chemotherapy, being free of disease at 21 moths of follow-up.

Rendimiento diagnóstico y hallazgos con la cápsula endoscópica en pacientes con sangrado digestivo de origen oscuro en la Clínica Universitaria San Juan de Dios en Cartagena, Colombia / Diagnostic Performance of, and findings from, Capsule Endoscopy for patients with Gastrointestinal Bleeding with Obscure Origins at the Clínica Universitaria San Juan de Dios in Cartagena, Colombia

Introducción: La cápsula endoscópica (CE) es, actualmente, el estudio de primera elección en la exploración del sangrado digestivo oscuro (SDO), después de una esofagogastroduodenoscopia (EGD) y una ileocolonoscopia negativas. Objetivo: Evaluar el rendimiento diagnóstico y los hallazgos en el intestino delgado en 50 pacientes con sangrado digestivo de origen obscuro en nuestra institución. Materiales y métodos: Estudio observacional descriptivo retrospectivo, en una cohorte de pacientes que consultaron por SDO a la Clínica Universitaria San Juan de Dios en la ciudad de Cartagena, del 1 enero del 2010 al 31 abril del 2013. El rendimiento diagnóstico de la CE fue definido por la presencia de lesiones altamente significativas (P2), poco significativas (P1) y normales (P0). Para el análisis de los resultados se utilizó el software STATA 11.0. Resultados: Se incluyeron 50 pacientes con SDO. De estos, 34 casos con SDO evidente (68%) y 16 con SDO oculto (32%). El 62% (31) de sexo femenino, con una edad promedio de 60,14 años, DE±20,02 (20 a 87 años). La CE se realizó de manera ambulatoria en 26 casos (52%) e intrahospitalaria en 24 casos (48%). El rendimiento diagnóstico de la CE en el SDO (lesiones P2) fue de 58% (29/50). En SDO evidente 61,74%(21/34) y en SDO oculto 50% (8/16). La preparación fue adecuada en el 92% de los casos. La exploración completa del intestino delgado se logró en el 96%. Hubo una retención de la cápsula en dos pacientes. Las lesiones P2 encontradas en el intestino delgado fueron vasculares en 51,9%, tumorales en 20,6%, parasitarias en 13,7%, en lesiones ulcerosas e inflamatorias 6,9% y en divertículos 6,9%. Las lesiones P2 responsable del SDO por fuera del intestino delgado, al alcance de una EGD y colonoscopia, se encontraron en el 24,13%(7/29), una en el esófago, 2 en el estómago, una en el duodeno y 3 en el colon derecho. Conclusión: La rentabilidad diagnóstica de la CE en nuestra serie fue del 58%. Las lesiones vasculares ...

Introduction: Capsule endoscopy (CE) is currently the study of choice for the exploration of Obscure gastrointestinal bleeding (OGIB) after obtaining negative results from esophagogastroduodenoscopy (EGD) and ileocolonoscopy. Objective: The objective of this study was to evaluate the diagnostic yield and findings from capsule endoscopy studies of the small intestines of 50 patients with gastrointestinal bleeding of obscure origin in our institution. Materials and methods: This was a retrospective, descriptive and observational study of a cohort of patients seen for OGIB at the Clínica Universitaria San Juan de Dios in Cartagena from January 1, 2010 to April 31, 2013. Diagnostic yields from CE were categorized as highly significant lesions (P2), insignificant lesions (P1), and normal (P0). STATA 11.0 software was used to analyze results. Results: Fifty patients suspected of having OGIB were included: 34 (68%) obvious cases and 16 (32%) cases of occult OGIB. Thirty-one (62%) of the patients were women 62%, and the mean patient age was 60.14 ± 20.02 years with an age range of 20 to 87 years. CE was performed on an outpatient basis in 26 cases (52 %) and in-hospital in 24 cases (48%). The diagnostic yield of CE for diagnosing OGIB (P2 lesions) was 58 % (29/50). It was 61.74 % (21/34) for obvious OGIB and 50 % (8/16) for occult OGIB. The preparation was suitable in 92% of the patients. Complete examination of the small intestine was achieved in 96% of the cases. Two patients retained the capsules. 51.9 % of the P2 lesions found were vascular, 20.6 % were tumors, 13.7 % were parasitic, and ulcerative lesions and inflammatory diverticula accounted for 6.9 % of the lesions each. P2 lesions which were responsible for OGIB, but which were outside of the ranges of EGDs and colonoscopy, were found in 24.13 % (7/29) of the patients. One was in a patient’s esophagus, two were in patients’ stomachs, one in a patient’s duodenum, and three patients had them in their right colons. Conclusion: The diagnostic yield of CE in our series was 58%. Vascular lesions (angiodysplasia) were the leading cause of bleeding which is a result that is comparable to other publications internationally and in Colombia. One striking result of our study was that the second causes of OGIB were tumors and parasitic infestations in the population studied.

An Unusual Cause of Gastrointestinal Hemorrhage: Gastrocolic Fistula Caused by Colon Cancer Invasion / 영남의대학술지

Gastrocolic fistula is a fistulous communication between the stomach and the colon. It is a passage between the gastric epithelium and the colonic epithelium. This uncommon complication is caused by benign and malignant diseases of the stomach or the colon. Its clinical manifestations include weight loss, diarrhea and fecal vomiting; occasionally, anemia, poor oral intake, fatigue and dizziness; and very rarely, gastrointestinal bleeding. In this paper, an unusual case of gastrocolic fistula accompanied by hematochezia, which was revealed to have been caused by colon cancer invasion, is described.

Intestinal Paragonimiasis with Colonic Ulcer and Hematochezia in An Elderly Taiwanese Woman

A 94-year-old female with end-stage renal disease presents with fever, fatigue, and hematochezia. She had previously resided in Hunan Province, China, and Myanmar, and she immigrated to Taiwan 30 years ago. Colonoscopy revealed a colonic ulcer. Biopsy of the colonic ulcer showed ulceration of the colonic mucosa, and many Paragonimus westermani-like eggs were noted. Serum IgG antibody levels showed strong reactivity with P. westermani excretory-secretory antigens by ELISA. Intestinal paragonimiasis was thus diagnosed according to the morphology of the eggs and serologic finding. After treatment with praziquantel, hematochezia resolved. The present case illustrates the extreme manifestations encountered in severe intestinal paragonimiasis.

Jejunal Variceal Bleeding Successfully Treated with Percutaneous Coil Embolization

A 52-yr-old male with alcoholic liver cirrhosis was hospitalized for hematochezia. He had undergone small-bowel resection due to trauma 15 yr previously. Esophagogastroduodenoscopy showed grade 1 esophageal varices without bleeding. No bleeding lesion was seen on colonoscopy, but capsule endoscopy showed suspicious bleeding from angiodysplasia in the small bowel. After 2 weeks of conservative treatment, the hematochezia stopped. However, 1 week later, the patient was re-admitted with hematochezia and a hemoglobin level of 5.5 g/dL. Capsule endoscopy was performed again and showed active bleeding in the mid-jejunum. Abdominal computed tomography revealed a varix in the jejunal branch of the superior mesenteric vein. A direct portogram performed via the transhepatic route showed portosystemic collaterals at the distal jejunum. The patient underwent coil embolization of the superior mesenteric vein just above the portosystemic collaterals and was subsequently discharged without re-bleeding. At 8 months after discharge, his condition has remained stable, without further bleeding episodes.

A Case of Small Bowel Lymphangiectasia that Presented with Gastrointestinal Bleeding and was Treated by Small Bowel Resection / 대한내과학회지

Intestinal lymphangiectasia (IL) is a rare disorder, characterized by dilatation of intestinal lymphatics and leakage from ruptured lacteals to the intestinal lumen. Primary IL may be due to a congenital malformation of the lymphatic system, whereas secondary IL is caused by decreased lymph flow from thoracic ductsdue to elevated left subclavian vein pressure as a result of a preceding inflammatory or neoplastic disease. IL can present as protein-losing enteropathy with clinical manifestations of hypoproteinemia, hypoalbuminemia, edema, ascites, or pleural effusions. In very rare cases, it can present as severe intestinal bleeding. We experienced a 48-year-old woman presenting with recurring hematochezia and melena. She was diagnosed bydouble balloon enteroscopy, and surgical resection was needed to stop bleeding. In conclusion, IL can present clinically as painless chronic blood loss. If IL is locally distributed, surgical resection may be needed to control bleeding and to exclude other underlying causes in some patients.

Jejunal Metastasis of Lung Cancer Diagnosed with Double Balloon Enteroscopy / 대한소화기내시경학회지

Metastasis from lung cancer to the small bowel is rare and this accounts for 0.2% to 0.5% of all the cases of metastasis from lung cancer. In most cases, the patients are asymptomatic and they can show signs of bleeding, intestinal obstruction, perforation and so on. A better diagnostic approach to the small bowel has recently been made possible through capsule endoscopy and double balloon enteroscopy (DBE), and they have a higher diagnostic rate for small bowel bleeding compared with that of the previous diagnostic tests. DBE makes it possible to diagnose precisely due to the high quality endoscopic images and biopsy specimens. In addition, therapeutic DBE with a 2.8 mm channel enables performing more kinds of therapeutic procedures than diagnostic DBE with a 2.2 mm channel. If small bowel metastasis is suspected on 18FDG-PET/CT, then DBE can be considered for making a pathologic diagnosis. We report here on a case of small bowel metastasis from non small cell lung cancer in a 39-year-old woman who complained of hematochezia and we review the relevant literature.